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Microbiomes At Guelph

Exploring the next frontier in human, animal, plant, and soil health

The study of microbial interactions has undergone a massive paradigm shift in recent years. Whereas the study of microbes once focused mainly on individual species, we now recognize that the collective and synergistic effects of “communities of microorganisms” – aka microbiomes –  have an enormous impact on their environment. From soils and plants to  humans and animals, microbiomes have the ability profoundly shape their host environment in both positive and negative ways.

This paradigm shift has led to an explosion in microbiome research around the world. Ten years ago, there were just over 2,000 papers on microbiome and health alone; today there are over 44,000 with new discoveries emerging every day. Many have called microbiomes the “next frontier” in the life sciences.

At the University of Guelph, a growing number of researchers are exploring the power of microbiomes to transform the way we produce food, manage the environment and maintain (or restore) human and animal health.  These researchers are building on noted areas of research strength at UofG (soil and food science, plant and animal agriculture, molecular biology and bioinformatics) to shed light on how microbiomes influence essential biological functions. They are aided by advanced molecular technologies (‘omics) that vastly expand our ability to understand how microbes are connected to each other and their host, and novel approaches to culturing microbes once thought “unculturable” (e.g., see Dr. Emma Allen-Vercoe describe her pioneering human bioreactor system, the “Robogut”, here).

Microbiomes at Guelph (MAG) is a new working group that brings together approximately 45 faculty members from different disciplines and departments at UG who share the goal of advancing knowledge and innovation in the field of microbiome science.  MAG provides a platform for sharing information and resources, facilitating new collaborations, and enhanced opportunities for HQP training and networking.  For a full list of current faculty members, see our Members page.

Learn more about microbiome research by MAG members by exploring our “Research” section.

For more information about MAG or if you are a UG researcher who would like to join the working group, please see our “Contact” page.


VISION

In our vision, Microbiomes at Guelph will harness the power of microbiomes to develop innovative solutions to pressing challenges in human and animal health, soil remediation, sustainable agriculture and food safety.

MISSION

Our mission is to support leading edge microbiome research across diverse disciplines by developing novel  research tools and approaches, leveraging our multidisciplinary expertise to address complex research questions, and sharing resources and  infrastructure to accelerate discovery.


Harnessing the microbiome: examples of MAG projects

Interaction between circadian system, gut microbiome and cardiac repair following heart attacks

Role of microbiome dysfunction in the etiology of colorectal cancer and Parkinson’s disease

Improvement of honeybee health through management of the bee gut microbiome

Feeding strategies to improve gut health and disease resistance in poultry, swine and farmed fish

Role of the skin microbiome in innate immunity

Ethical implications of human microbiome research and its applications

Development of soil microbiome-based approaches to remediating contaminated soils

Treatment of inflammatory bowel disease in dogs with fecal transplants

Impacts of stress on wildlife microbiomes 

Influence of food additives on the gut microbiome

Development of novel, microbial-based approaches to protect crops from abiotic stress and pathogens

Inheritance and transmission of plant microbiomes


Our Collaborators

Within Canada

And beyond…


Latest News

MAG researchers in the news: New research points to a yet-unexplored “nitrate-gut-heart axis,” underlining the importance of gut health to overall health and well-being. Read the full story here.

MSc thesis defense: next Tuesday January 10, 2023, 1:00 pm ET, Maddison Arsenault (supervised by Dr. Brandon Lillie) will defend their work titled “Pig fecal microbiota during early stages of production and associations with sow microbiota, genotype, and growth performance.” The event is virtual; click here for the link


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